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格拉司琼和恩丹西酮防治儿童淋巴瘤患者化疗所致呕吐的对比研究
引用本文:陈建祥,双跃荣,万丽娟,管彗红. 格拉司琼和恩丹西酮防治儿童淋巴瘤患者化疗所致呕吐的对比研究[J]. 赣南医学院学报, 2005, 25(2): 139-140
作者姓名:陈建祥  双跃荣  万丽娟  管彗红
作者单位:江西肿瘤医院肿瘤内科,江西,南昌,330029;江西肿瘤医院肿瘤内科,江西,南昌,330029;江西肿瘤医院肿瘤内科,江西,南昌,330029;江西肿瘤医院肿瘤内科,江西,南昌,330029
摘    要:
目的:观察格拉司琼与恩丹西酮防治儿童淋巴瘤患者因化疗所致呕吐的效果和副反应。方法:89例淋巴瘤患者分为格拉司琼和恩丹西酮两组。格拉司琼组43例,化疗前静脉点滴3mg,用1次。恩丹西酮组46例,化疗前静脉给予恩丹西酮4mg,用1次。结果:两组止吐有效率(0-2次呕吐)分别为93.0%、91.3%。副反应轻,可以耐受。结论:恩丹西酮与格拉斯琼的疗效一样。儿童应用安全有效。

关 键 词:格拉司琼  恩丹西酮  淋巴瘤  儿童
文章编号:1001-5779(2005)02-0139-02
修稿时间:2005-02-26

Comparative Study on Ondansetron and Granisetron in the Prophylaxis of Emesis Induced by Chemotherapy in Children with Lymphoma
CHEN Jian-xiang,SHUANG Yue-rong,WANG Li-juan,et al. Comparative Study on Ondansetron and Granisetron in the Prophylaxis of Emesis Induced by Chemotherapy in Children with Lymphoma[J]. Journal of Gannan Medical College, 2005, 25(2): 139-140
Authors:CHEN Jian-xiang  SHUANG Yue-rong  WANG Li-juan  et al
Abstract:
Objective:To observe efficacy of granisetron and ondansetron in the prophylaxis of emesis induced by chemotherapy in children with lymphoma. Methods:A total 89 patients were divided into two groups, granisetron (3mg)and ondansetron(4mg)were administered intravenously respectively during chemotherapy.Results:The effective control rate (0-2 emetic episodes a day)of two groups was 93.0%,91.3% respectively. Adverse effects were mild and tolerable. Conclusion:Ondansetron is as effective as granisetron. They are effective and safe for children.
Keywords:Ondansetron  Granisetron  Lymphoms  Children
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