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| 紫外系数倍率法测定雷尼替丁血药浓度 | |
| 引用本文： | 兰丙欣,李广胜,汪建生.紫外系数倍率法测定雷尼替丁血药浓度[J].中国药房,2002,13(6):367-368. |
| 作者姓名： | 兰丙欣 李广胜 汪建生 |
| 作者单位： | 1. 河南省许昌市中心医院,许昌市,461000 2. 河南中医学院医院药剂科,郑州市450008 3. 河南省许昌市药品检验所,许昌市,461000 |
| 摘 要： | 目的 :测定雷尼替丁血药浓度。方法 :采用紫外系数倍率法 ,以甲醇作对照液 ,在波长200nm～400nm范围内扫描 ,选定λ1=324nm、λ2=358nm ,绘制工作曲线。结果 :口服雷尼替丁血药浓度有明显的双峰现象。结论 :本方法简便 ,适宜于基层单位进行血药浓度检测。 |
| 关 键 词： | 紫外系数倍率法 雷尼替丁 血药浓度 |
| 文章编号： | 1001-0408(2002)06-0367-02 |
| 修稿时间： | 2001年8月29日 |
Determination of the Concentration of Ranitidine in Serum by the Method of Multipled Ultraviolet Coefficient |
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| LAN Bingxin.Determination of the Concentration of Ranitidine in Serum by the Method of Multipled Ultraviolet Coefficient[J].China Pharmacy,2002,13(6):367-368. | |
| Authors: | LAN Bingxin |
| Abstract: | OBJECTIVE:To determine the concentration of ranitidine in serum METHODS:To use the method of multipled ultraviolet coefficient,the concentration of ranitidine in serum was scanned with detective wavelengths from 200nm to 400nm,and the work-curve was made with detective wavelengths at 324nm and 358nm RESULTS:Ranitidine taken orally resulted in an obvious double-peak in blood concentration CONCLUSION:The method is simple and quick,and is fit for the determination of serum concentration of ranitidine in basic units |
| Keywords: | multipled ultraviolet coefficient ranitidine concentration of drug in serum |
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