In vitro antibacterial activity of Desmodium gangeticum (L.) DG |
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| Authors: | Krishnasamy Karthikeyan Gandhi Siddhar Selvam Rajendran Srinivasan Chidambaram Chandran Subramaniyan Kulothungan |
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| Affiliation: | 1. Department of Pharmacognosy, SDM Centre for Research in Ayurveda and Allied Sciences, Laxminarayana Nagar, Kuthpady, Udupi, Karnataka, India.;2. Department of Phytochemistry, Captain Srinivasa Murthi Drug Research Institute for Ayurveda (CCRAS), Arignar Anna Government Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, India.;3. Department of Plant Biology and Biotechnology, Former Dean of Science, Presidency College (Autonomous), Chennai, Tamil Nadu, India.;4. Department of Biochemistry, Captain Srinivasa Murthi Drug Research Institute for Ayurveda (CCRAS), Arignar Anna Government Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, India.;5. Department of Experimental Medicine, SDM Centre for Research in Ayurveda and Allied Sciences, Laxminarayana Nagar, Kuthpady, Udupi, Karnataka, India. |
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| Abstract: | ![]()
ObjectiveTo identify the antibacterial activity of Desmodium gangeticum (D. gangeticum).MethodsAntibacterial activity of D. gangeticum was tested with various solvents viz., methanol, ethanol, chloroform and aqueous extract against various bacterial pathogens such as Klebsiella pneumoniae, Escherichia coli, Salmonella typhi, Streptococcus mutants and Pseudomonas aeruginosa. Antibiotic sensitivity assay was performed with amoxicillin, kanamycin, tetracyclin, ciprofloxacin and penicillin.ResultOf the selected several extract, the methanolic extract showed maximum zone of inhibition (24±2.3mm) against S. mutants and minimum zone of inhibition was observed with aqueous extract against P. aeruginosa (7±0.08). In addition the antibiotic sensitivity was observed with kanamycin, tetracyclin, ciprofloxacin against all bacterias.ConclusionsThe methonalic extract of D. gangeticum be able to use as potential antibacterial source for various infective pathogens. |
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