慢性鼻窦炎内窥镜手术上颌窦粘膜扫描电镜观察

为了对行内窥镜鼻窦手术的慢性鼻窦炎患者上颌窦粘膜的术后超微结构变化进行评价，利用扫描电镜及图像分析技术对１６例（２０侧）术中和术后上颌窦粘膜及自然孔粘膜的纤毛面积进行定量测定。发现术前上颌窦及其自然孔粘膜纤毛细胞明显减少，杯状细胞，微绒毛细胞增多，部分病例有鳞状上皮化生。术后６个月￣１年，大部分病例受损的纤毛细胞明显恢复，纤毛细胞覆盖面积增加，有统计学意义，通过内窥镜手术，改善上颌窦的通气、引流、

Scanning electron microscopic changes of maxillary sinus mucosa before and after functional endoscopic sinus surgery]

We attempted to evaluate postoperative maxillary sinus mucosal changes in 20 maxillary sinuses of 16 patients who underwent functional endoscopic sinus surgery (FESS). Ciliated area of the maxillary sinus mucosa and ostium of maxillary sinus were quantitatively observed by scanning electron microscope and image analysis before and after FESS. In the present study, the number of preoperative ciliated cells of maxillary sinus mucosa and ostium was significantly reduced, goblet cells and microvillous cells were increased, and squamous cell metaplasia observed in part of the maxillary sinuses. Many damaged ciliated cells tend to recover and ciliated area significantly increased at 6-12 months after the surgery. The results showed that the damaged ciliated epithelium could return to normal by the improvement of ventilation and drainage of the maxillary sinus following FESS.