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Immunohistological localization of melatonin in the pineal gland and retina of the rat
Authors:Kirsten Mennenga  Manfred Ueck  Russel J. Reiter
Affiliation:Institute of Anatomy and Cytobiology, Justus Liebig University, Giessen, FRG.
Abstract:
An incubation procedure for the demonstration of melatonin is described using freeze-dried, unfixed material embedded in vacuum directly in glycolmethacrylate. The results indicate the binding of melatonin in the nucleus of pineal parenchymal cells and in the outer nuclear layer of the retina of rats; binding is greater at night than during the day.
Keywords:immunocytochemistry    melatonin binding sites    melatonin receptors    pinealocyte    photoreceptor cell
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