新生血管性青光眼不同治疗方案的临床疗效比较研究

目的 探讨不同治疗方案对新生血管性青光眼(NVG)患者临床疗效的影响差异。方法回顾分析42例(42眼)行单纯手术治疗的NVG患者(对照组)和同期予以药物联合手术方案的42例(42眼)NVG患者(研究组)临床资料。比较两组术后6个月时功能性滤过泡形成率、治疗成功率及新生血管消退率、复发率差异,记录其治疗前后眼压变化情况。结果术后6个月时,研究组功能性滤过泡形成率及治疗成功率均明显高于对照组。两组术后新生血管消退率及复发率比较,差异均无显著性。治疗后3个月、6个月时,两组眼压检测结果均明显低于同组治疗前,且研究组眼压检测结果明显低于同时段对照组。结论康柏西普玻璃体腔注射联合手术治疗能有效降低NVG患者眼压,对促进术后功能性滤过泡形成等具有积极意义。

Comparison of the clinical efficacy of different therapeuticregimens for neovascular glaucoma

Objective To compare the efficacy of different regimens for neovascular glaucoma (NVG).MethodsThe clinical data of 42 cases (42 eyes) of NVG patients treated with surgery alone (control group) and 42 cases (42 eyes) of NVG patients treated with drugs combined with surgery in the same period (study group) were retrospectively analyzed.The formation rate of functional bleb,success rate of treatment,the regression rate of new vessels and recurrence rate were observed and compared between the two groups at 6 months after surgery.The changes of intraocular pressure before and after treatment were recorded.Results6 months after surgery,the formation rate of functional bleb and success rate of treatment were significantly higher in the study group than the control group.There was no significant difference in the regression rate of new blood vessels and recurrence rate between the two groups.3 months and 6 months after treatment,the intraocular pressure of the two groups were significantly lower than the same group before treatment,and the intraocular pressure of the study group was significantly lower than the control group in the same time period.ConclusionIntravitreal injection of conbercept combined with surgery can effectively reduce the intraocular pressure of patients with diabetic NVG,which is of positive significance in promoting the formation of functional bleb after surgery.