基于ReHo方法的大学生网络成瘾静息功能磁共振成像研究

目的:探讨网络成瘾大学生静息状态脑功能特点。方法:采用ReHo分析方法 ,19名网络成瘾大学生及19名对照进行磁共振脑功能成像,比较两组平均脑ReHo图的差异。结果:IAD组ReHo值升高区域主要集中在小脑、脑干、扣带回(右侧)、双侧海马旁回、右侧额叶(直回,额中回及额下回)、左侧额上回、左侧楔前叶、右侧中央后回、右侧枕中回、右侧颞下回、左侧颞上回及颞中回;ReHo降低的区域仅表现在左侧顶叶的楔前叶。结论:网络成瘾大学生局域一致性存在异常,大部分脑区同步性增强,小脑、脑干、边缘叶、额顶叶同步性增强可能与网络成瘾奖赏通路有关。

Resting fMRI Study of IAD College Students Based on Method of ReHo Analysis

Objective: To analyze encephalic functional characteristic of IAD college students in the resting state.Methods: 19 IAD college students and 19 controls performed fMRI in the resting state.ReHo method is adopted to analyze the difference between the average ReHo in two groups.Results: IAD showed increased and decreased brain regions in ReHo in the resting state compared with controls.The increased ReHo was distributed over the cerebellum,brainstem,right cingulate gyrus,bilateral parahippocampus,right frontal lobe(rectal gyrus,inferior frontal gyrus and middle frontal gyrus),left superior frontal gyrus,left precuneus,right postcentral gyrus,right middle occipital gyrus,right inferior temporal gyrus,left superior temporal gyrus and middle temporal gyrus.The decresed ReHo was only found in left precuneus.Conclusion: Abnormal brain activity of IAD college students may exist in a resting state compared with the controls.Enhancement of synchronization among brainstem,limbic lobe,frontal lobe,parietal lobe may be related to reward pathways.