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| 酸化甘油溶解试验在儿科临床的应用 | |
| 引用本文： | 吴明 范卫明. 酸化甘油溶解试验在儿科临床的应用[J]. 临床血液学杂志, 1992, 5(4): 163-165 |
| 作者姓名： | 吴明 范卫明 |
| 作者单位： | 上海医科大学儿科研究所，上海医科大学儿科研究所，上海医科大学儿科研究所，上海医科大学儿科研究所，上海医科大学儿科研究所 邮政编码 200032，邮政编码 200032，邮政编码 200032，邮政编码 200032，邮政编码 200032 |
| 摘 要： | 本文报道20例遗传性球形细胞增多症(HS),15例溶血性贫血(溶贫)及45例正常初生～12岁小儿微量外周血酸化甘油溶解试验测定值(AGLT_(50)),20例HS AGLT_(50)均<100秒。14例溶贫及45例正常小儿AGLT_(50)均>290秒。与红细胞渗透脆性试验等其它有关实验室指标比较,AGLT对HS诊断具有一定特异性及敏感性。适合儿科临床应用,并适用于HS家系调查。 |
| 关 键 词： | 酸化甘油 遗传性 球形细胞增多 |
Clinical Use Acidified Glycerol Lysis Test (AGLT) in Pediatrics |
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| Wu Yue,Fan Wei-ming,Shen Wei-min,et alPediatric Institute,Shanghai Medical University. Clinical Use Acidified Glycerol Lysis Test (AGLT) in Pediatrics[J]. Journal of Clinical Hematology, 1992, 5(4): 163-165 | |
| Authors: | Wu Yue Fan Wei-ming Shen Wei-min et alPediatric Institute Shanghai Medical University |
| Abstract: | Using micro peripherol blood sample, we study the AGLT in 20 cases ofhereditary spherocytosis (HS), 15 cases of hemolytic anemia and 45 cases of healthy chil-dren from newborm to 12 years old. 20 cases of HS AGLT_(50)<100s, 14 cases of hemolyticanemia and 45 cases of healthy control AGLT_(50)>290s. Compared the AGLT with the os-motic fragility and the other laboratory methods, AGLT is a specific and sensitive test fordiagnosis of HS. This assay is suitable for pediatric clinical use and screening of HS pedi-gree. |
| Keywords: | Acidified glycerol lysis test Hereditary spherocytosis Peripheral blood |
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