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关于Reed-Frost模型的研究和改进
引用本文:梅家模,曾光.关于Reed-Frost模型的研究和改进[J].中华流行病学杂志,1994(2).
作者姓名:梅家模  曾光
作者单位:江西省卫生防疫站,中国预防医学科学院流行病学微生物学研究所
摘    要:笔者提出了对Reed-Frost模型的学术评论,并新建了一种Reed-Frost模型的改进模型。该改进模型全面考虑了隐性感染者的产生、传染作用及向免疫者的转化。应用这个模型,模拟了NewEngland的麻疹流行和中国上海市某保育院的水痘流行,结果颇为理想。该模型包括了基本的流行要因,故能用以解释流行过程,并可帮助流行病学工作者理解隐性感染在传染病流行过程中的作用。

关 键 词:Reed-Frost模型,流行,隐性感染

Study and Improvement of Reed-frostModel
Mei Jiamo,Zeng Guang.,JiangxiProvinial Hygiene and Epidemic Pre-vention Station,Nanchang.Study and Improvement of Reed-frostModel[J].Chinese Journal of Epidemiology,1994(2).
Authors:Mei Jiamo  Zeng Guang  JiangxiProvinial Hygiene and Epidemic Pre-vention Station  Nanchang
Institution:Mei Jiamo,Zeng Guang.,JiangxiProvinial Hygiene and Epidemic Pre-vention Station,Nanchang 330046
Abstract:he purpose of this paper is to modifythe Reed-Frost theory of epidemics withthe underlying assumptions of the modelincluding the occurrence of inapparent in-fections,and their influence on the course of the epidemic.With this model two epidemics were computed;(1)the Aycock outbreak of measles in a New England boy-boarding school in 1934;(2)the out-break of chickenpox in a Shanghai kinder-garten in 1950.The calculated and ob-served results were well in agreement A substantial improvement in fitness was shown as measured by chi-square tests.As presented,the model offers a rea- sonably good explanation on the occurren-ce of inapparent infections and its effect on the pattern of the disease.
Keywords:Reed-Frost model Epidemic-Inapparent infection  
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