硫酸氨基葡萄糖结合关节腔内注射透明质酸钠治疗膝骨关节炎的疗效观察

目的 探讨硫酸氨基葡萄糖结合关节腔内注射透明质酸钠对治疗膝骨关节炎的临床效果。方法 膝骨关节炎患者98例,随机分成两组,治疗组和对照组,治疗组49例给予口服硫酸氨基葡萄糖加关节腔内注射透明质酸钠,对照组49例单纯给予关节腔内注射透明质酸钠,观察两组的临床疗效。结果 治疗组总有效率93.9%,对照组总有效率81.6%,治疗组高于对照组,差异有统计学意义（P〈0.05）。结论 硫酸氨基葡萄糖结合关节腔内注射透明质酸钠可以提高膝骨关节炎的疗效。

Clinical observation on knee osteoarthritis treated with glucosamine sulfate and sodium hyaluronate injecting into knee joint

Objective To observe the clinical effect of knee osteoarthritis treated with glucosamine sulfate and hyaluronate injecting into knee joint. Methods Divided 98 cases of patient With knee osteoarthritis into two groups. 49 cases in each group, treatment group was treated with oral glucosamine sulfate and articular cavity injection of sodium hyaluronate, control group was treated with sodium hyaluronate alone, clinical effects of two groups were observed. Results The clinical effect of treatment group and control group were 93.9% and 81.6%, there was a significant difference between these two groups（P〈0.05）. Conclusion Combined glucosamine sulfate with sodium hyaluronate injecting into knee joint can improve the clinical effect of knee osteoarthritis.