醒脑静注射液治疗急性脑梗死伴意识障碍患者的临床研究

目的 观察醒脑静注射液对急性脑梗死伴意识障碍患者的临床疗效.方法 86例急性脑梗死伴意识障碍的患者随机分为治疗组45例和对照组41例,对照组患者采用常规治疗方法,治疗组患者在常规治疗的基础上加用醒脑静注射液20mL静脉滴注,两组患者疗程均为14 d.比较治疗前后两组患者的临床疗效、血液流变学、血浆超敏C反应蛋白（hs-CRP）、格拉斯哥昏迷评分（GCS）及住院天数.结果 治疗组临床总有效率为88.89％,对照组为65.85％,治疗组疗效优于对照组（P＜0.05）;治疗组患者格拉斯哥昏迷评分、血液流变学、hs-CRP及住院天数均优于对照组患者,差异有显著性（P＜0.05）;治疗中不良反应轻微.结论 醒脑静注射液联合常规方法治疗急性脑梗死伴意识障碍患者的临床疗效优于单纯常规治疗.

Clinical Effect of Xingnaojing Injection on the Treatment of Acute Cerebral Infarction Patients with Disorders of Consciousness

Objective： To observe the clinical effect of Xingnaojing Injection on the treatment of acute cerebral infarction patients with disorder of consciousness. Methods： 86 patients were randomly divided into one treatment group with 45 patients and one control group with 41 patients. The control group was treated with conventional treatment while the treatment group was added with Xingnaojing Injection 20mL by intravenous drip besides the conventional treatment. Both groups had a 14 - day course of treatment. The clinical curative effect, blood rheology, serum high sensitivity C reactive protein （ hs - CRP）, Glasgow coma score （GCS） and the period of hospitalization of the two groups were compared before and after the treatment. Results： The total effective rate of the treatment group was 88. 89% while that of the control group was 65.85%. The treatment group was better than the control group （P 〈0.05）. The glasgow coma score, blood rheology, hs - CRP and hospital stay of the treatment group were better than that of the control group. There was significant difference （P 〈 0.05 ） and a mild adverse reactions in the treatment. Conclusion ： Xingnaojing Injection combined with a conventional method has a better effect on the treatment of acute cerebral infarc- tion patients with disorder of consciousness.