ICU鲍曼不动杆菌感染分布及耐药性分析

目的分析我院重症监护病房(ICU)内鲍曼不动杆菌(AB)标本分布、耐药情况、感染的危险因素及临床抗菌药物使用情况,为预防与治疗AB感染提供依据。方法对2011年我院ICU分离的41株AB标本(主要来源于痰标本85.37%)的分布、耐药情况及易感AB的危险因素和临床抗菌药物使用情况进行回顾性分析。结果 AB敏感率较高的是头孢哌酮舒巴坦(100%)、亚胺培南(92.5%),对其他抗菌药物的耐药率严重。结论鲍曼不动杆菌对各种抗菌药物的耐药性逐渐增强,多重耐药和泛耐药鲍曼不动杆菌分离率高;应警惕并高度重视该菌感染及耐药监测,以减少耐药菌株的产生和播散。

Analysis on clinical distribution and drug resistance of Acinetobacter baumannii in ICU

Objective To investigate the clinical distribution and drug resistance of Acinetobacter baumannii and provide useful help for the prevention and treatment of A.baumannii infection.Methods A total of 41 nonduplicate strains of A.baumannii were collected from a crtain hospital’s ICU in 2011.The basic information,drug susceptibility and the use of antibiotics in patients were retrospectively analyzed.Results 41 strains of A.baumannii mainly came from the sputum samples of patients(85.37%).It was showed that the sensitive drugs of Acinetobacter baumannii were cefoperazone sodium and sulbactam sodium and imipenem.The resistant drugs of Acinetobacter baumannii were aminoglycosides,quinolones,and bets-lactamases.Conclusion Antimicrobial resistance of A.baumannii and the isolation rate of multidrug-resistant and pandrug-resistant A.baumannii are increasing.So we must keep an eye on A.baumannii infection and its drug-resistance changes in order to prevent the emergence and spread of drug-resistant strains.