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高效液相色谱法测定双石清热合剂中绿原酸含量
引用本文:吕彬,宋太民. 高效液相色谱法测定双石清热合剂中绿原酸含量[J]. 中国药业, 2007, 16(15): 25-25
作者姓名:吕彬  宋太民
作者单位:1. 河南省漯河市药品检验所,河南,漯河,462008
2. 河南省漯河市中心医院,河南,漯河,462000
摘    要:
目的 测定双石清热合剂中绿原酸的含量.方法 采用高效液相色谱(HPLC)法测定.结果 绿原酸质量浓度的线性范围为0.0100-0.1000 mg/mL,平均回收率为98.8%,RSD=1.3%.结论 方法准确、简便、易行,可用于该制剂的质量控制.

关 键 词:双石清热合剂  高效液相色谱法  绿原酸
文章编号:1006-4931(2007)15-0025-01
修稿时间:2006-10-162007-01-22

Determination of Chlorogenic Acid in Shuangshiqingre Oral Solution by HPLC
Lu Bin,Song Taimin. Determination of Chlorogenic Acid in Shuangshiqingre Oral Solution by HPLC[J]. China Pharmaceuticals, 2007, 16(15): 25-25
Authors:Lu Bin  Song Taimin
Affiliation:1. Luohe Institute for Drug Control of Henan Province, Luohe, Henan, China 462008; 2. Luohe Central Hospital of Henna Province, Luohe, Henan, China 462000
Abstract:
Objective To determine the content of chlorogenic acid in Shuangshiqingre oral solution.Methods To establish a method using HPLC for the content determination.Results A good linearity of chlorogenic acid was obtained in the range of 0.010 0-0.100 0 mg/mL,the mean recovery rate was 98.8% (RSD=1.3% ).Conclusion This method is accurate,reproducible,simple and easy to operate.It can be used for the quality control of this preparation.
Keywords:Shuangshiqingre oral solution   HPLC   chlorogenic acid
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