Structures of the initial bodies of trachoma inclusion as revealed in section by electron microscopy |
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| Authors: | MITSUI Y SUZUKI A HANABUSA J MINODA R OGATA S FUKUSHIMA S MIURA M |
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| Affiliation: | 1. Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, District of Chaoyang, Beijing, 100101, China;2. College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China;3. School of Economics and Management, Nanchang Aviation University, New District of Honggutan, Nanchang, 330063, China;1. Cubist Pharmaceuticals, 65 Hayden Ave., Lexington, MA 02421, United States;2. Evotec AG, Manfred Eigen Campus, Essener Bogen 7, 22419 Hamburg, Germany;3. Evotec (UK) Ltd., 114 Innovation Drive, Milton Park, Abingdon OX14 4RZ, UK;1. Centre for Preclinical Imaging, University of Liverpool, Liverpool, United Kingdom;2. Department of Neuroradiology, Walton Centre NHS Trust, Liverpool, United Kingdom;1. Department of Veterinary Biosciences, Faculty of Veterinary Medicine, PO Box 66, University of Helsinki, Finland;2. Department of Clinical Microbiology, University of Helsinki and Helsinki University Hospital, HUSLAB, Finland;3. Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, PO Box 57, University of Helsinki, Finland;4. Herttoniemi Veterinary Clinic, Hiihtomäentie 35, Finland;5. Pathology Research Unit, Finnish Food Safety Authority Evira, Mustialankatu 3, Helsinki, Finland |
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| Abstract: | ![]()
In the cytoplasm of conjunctival epithelial cells infected with trachoma virus there appear inclusions which contain at least four recognizable entities, i.e., initial bodies, polygons, elementary bodies, and minute bodies. The inclusion body may also contain an amorphous ground substance; this is presumably the carbohydrate matrix seen by light microscopy.The morphology of the initial bodies of trachoma and findings bearing on the intracellular development of the elementary bodies of trachoma are discussed. The elementary bodies of trachoma virus are also described in detail. The developmental course of these bodies is still obscure. |
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