海藻酸钠微球子宫动脉栓塞治疗子宫肌瘤

目的评价海藻酸钠微球在子宫肌瘤动脉栓塞治疗中的应用价值。材料与方法3例多发性子宫肌瘤患者施行了超选择性子宫动脉栓塞术。所用栓塞剂为直径500μm-700μm海藻酸钠微球。对栓塞前后子宫肌瘤的大小、数量、临床症状及体征,以及卵巢激素水平进行比较。术后1个月、3个月进行B超随访,术后3个月进行卵巢激素测定。以后每隔1年B超随访。结果3例多发子宫肌瘤患者,年龄40岁、41岁、43岁（平均41.5岁）。治疗前与治疗后三个月卵巢激素水平无明显变化。栓塞后1个月时症状明显好转,肌瘤缩小平均40%,其中4个小肌瘤消失。术后三个月肌瘤缩小50～60%,有5个小肌瘤消失。临床症状完全消失。平均每例随访42个月,未出现新的肌瘤,残留肌瘤体积随时间延长,逐渐变小。栓塞不良反应主要为疼痛、恶心、呕吐及发热。无严重不良反应发生。结论海藻酸钠微球用于子宫肌瘤动脉栓塞治疗方便、安全、疗效确切。

The Application of KMG in Artery Embolization for Uterine Fibroids

Objective To evaluate the therapeutic effect of KMG in uterine artery embolization for uterine fibroids. Meterials and Methods: Three patients with multi-uterine fibroids were performed uterine artery embolization with KMG(300 m -700 m). In all cases,the size, number, clinical symptom and sign of uterine fibroids, as well as the levels of ovary hormones were compared before and after artery embolization. The patients received sonographic follow-up at the first and the third months after the embolization, an...