| 无创正压通气联合丁苯酞对OSAHS患者认知障碍的疗效 |
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| 引用本文： | 朱晓颖,戈艳蕾,王红阳,刘聪辉,张慈,陈前程,李洪力,李真真,安国利,张嘉宾.无创正压通气联合丁苯酞对OSAHS患者认知障碍的疗效[J].实用药物与临床,2019,22(1):27-30. |
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| 作者姓名： | 朱晓颖 戈艳蕾 王红阳 刘聪辉 张慈 陈前程 李洪力 李真真 安国利 张嘉宾 |
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| 作者单位： | 华北理工大学附属医院呼吸科,河北 唐山,063000;华北理工大学附属医院内分泌科,河北 唐山,063000 |
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| 基金项目： | 河北省医学重点研究项目 |
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| 摘 要： | 目的探讨无创正压通气联合丁苯酞对阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea-hypopnea syndrome,OSAHS)患者认知障碍的疗效,为临床治疗提供一种新的思路。方法选取OSAHS合并认知障碍患者166例,按照随机数字表分组方法分为治疗组83例和对照组83例,治疗组给予无创正压通气联合丁苯酞治疗,对照组应用无创正压通气治疗,比较两组治疗前后各指标的变化。结果治疗后,治疗组与对照组各临床及血清学指标均较治疗前有所改善,组内比较差异有统计学意义(P <0. 05);治疗组各指标的差值较对照组增加,差异有统计学意义(P <0. 05)。结论无创正压通气及丁苯酞联合治疗较无创正压通气单独治疗能更有效地改善OSAHS患者的临床症状及认知障碍情况。
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| 关 键 词： | 阻塞性睡眠呼吸暂停低通气综合征 认知障碍 无创正压通气 丁苯酞 |
Effect of noninvasive positive pressure ventilation combined with butylphthalide on cognitive impairment in OSAHS patients |
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| ZHU Xiao-ying,GE Yan-lei,WANG Hong-yang,LIU Cong-hui,ZHANG Ci,CHEN Qian-cheng,LI Hong-li,LI Zhen-zhen,AN Guo-li,ZHANG Jia-bin.Effect of noninvasive positive pressure ventilation combined with butylphthalide on cognitive impairment in OSAHS patients[J].Practical Pharmacy and Clinical Remedies,2019,22(1):27-30. |
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| Authors: | ZHU Xiao-ying GE Yan-lei WANG Hong-yang LIU Cong-hui ZHANG Ci CHEN Qian-cheng LI Hong-li LI Zhen-zhen AN Guo-li ZHANG Jia-bin |
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| Institution: | (Respiratory Department,North China University of Science and Technology Affiliated Hospital,Tangshan 063000,China;Department of Endocrinology,North China University of Science and Technology Affiliated Hospital,Tangshan 063000,China) |
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| Abstract: | ZHU Xiao-ying;GE Yan-lei;WANG Hong-yang;LIU Cong-hui;ZHANG Ci;CHEN Qian-cheng;LI Hong-li;LI Zhen-zhen;AN Guo-li;ZHANG Jia-bin(Respiratory Department,North China University of Science and Technology Affiliated Hospital,Tangshan 063000,China;Department of Endocrinology,North China University of Science and Technology Affiliated Hospital,Tangshan 063000,China) |
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| Keywords: | Obstructive sleep apnea-hypopnea syndrome Cognitive impairment Noninvasive positive pressure ventilation Butyphthalide |
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