胃尔康治疗慢性萎缩性胃炎的临床及实验研究

本研究临床观察了胃尔康片对慢性胃炎（ＣＡＧ）脾胃阴虚证的疗效。采用单盲法，对照药为维酶素。两组服药前后作纤维胃镜及病理活检。结果：治疗组３２３例中临床治愈１１８例（３６．５３％），显效１３５例（４１．７９％），有效６１例（１８．８９％），无效９例（２．７９％）。总有效率９７．２１％。对照组１０５例中显效８例（７．６２％），有效３５例（３３．３３％），无效６２例（５９．０５％）；总有效率４０．９５％

Clinical and Experimental Study on Gastrosia Convalescens in Treating Chronic Atrophic Gastritis

Gastrosia convalescens(GC)is a new drug for treating the Spleen-Yin Deficiency syndrome of chronic atrophic gastritis(CAG).Animal experiment has shown that GC has the function of promoting the regeneration of atrophic glands,and that of anti-inflammation, reinforcing,strengthening the stomach etc.It has the effect on the intestinal electric activity in dogs,mainly exciting in action,which was superior than that of domperidoni(P<0.05).The result of clinical study has demonstrsted that the marked effective rate of GC was 78.32%,CAG reversed into chronic superficial gastritis(CSG) in 30.0% of patients(60/200 cases),CAG into chronic superficial atrophic gastritis(CSAC)in 39.0%(78/200 cases).and CSAG into CSG in 39.02%(48/123 cases).The disappearance rate of metaplasia of intestinal epithelium and atypical hyperplasia were 39.1% and 38.14% respectively.There was a very significant difference in comparing with control group(P<0.01).