Endometrial pathology associated with infertility among Nigerian women

SUMMARY: One hundred and forty endometrial specimens of women with infertility were examined with oil immersion at X100 magnification for evidence of secretory activity, presence of any inflammatory cells and characteristic features suggestive of specific pathogens. Twenty-three (16.4%) had evidence of chronic endometritis the majority being non-specific. Only two (1.4%) were granulomatous. There was a significant eosinophilic infiltrate in nine cases (6.4%) some numbering up to 55 eosinophils per 5 high power fields (5 hpf). Sensitive immunohistochemical techniques would be needed to correlate findings with specific pathogens for effective treatment.