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流式细胞仪检测IgA肾病患者尿巨噬细胞的临床意义
引用本文:朱国贞,李荣山,朱镭,齐悦,于为民,王利华,黄晓光,黄轶嵘,刘新艳. 流式细胞仪检测IgA肾病患者尿巨噬细胞的临床意义[J]. 临床医药实践, 2007, 16(4): 257-258
作者姓名:朱国贞  李荣山  朱镭  齐悦  于为民  王利华  黄晓光  黄轶嵘  刘新艳
作者单位:山西医科大学第二医院,山西,太原,030001
基金项目:山西省留学回国人员科研启动基金
摘    要:目的:研究尿巨噬细胞含量与IgA肾病(IgAN)患者肾脏功能损伤程度的关系。方法:用流式细胞仪(FCM)测定30例IgAN患者尿巨噬细胞含量,并与肾脏功能损伤程度进行对照。结果:轻度肾功能损伤组尿巨噬细胞含量为(10.5±2.7)%,中、重度肾功能损伤组尿巨噬细胞含量为(24.1±3.6)%,中、重度肾功能损伤组尿巨噬细胞含量明显高于轻度肾功能损伤组(P<0.05)。结论:尿巨噬细胞含量检测可作为协助判断IgAN肾功能损伤程度的指标之一。

关 键 词:巨噬细胞  流式细胞术  IgA肾病
文章编号:1671-8631(2007)04-0257-02
修稿时间:2006-12-25

The clinical significance in testing urinary macrophages in patients with IgA nephropathy by flowcytometry
ZHU Guo-zhen,LI Rong-shan,ZHU Lei,QI Yue,YU Wei-min,WANG Li-hua,HUANG Xiao-guang,HUANG Yi-rong,LIU Xin-yan. The clinical significance in testing urinary macrophages in patients with IgA nephropathy by flowcytometry[J]. Proceeding of Clinical Medicine, 2007, 16(4): 257-258
Authors:ZHU Guo-zhen  LI Rong-shan  ZHU Lei  QI Yue  YU Wei-min  WANG Li-hua  HUANG Xiao-guang  HUANG Yi-rong  LIU Xin-yan
Affiliation:The Second Hospital of Shanxi Medical University,Taiyuan 030001 ,China
Abstract:Objective:To find the correlation among urinary macrophages and degree of renal injury in patients with IgA nephropathy(IgAN).Methods:The content of urinary macrophage from 30 patients with IgAN was measured by flowcytometry.The data were compared with degree of renal injury.Results:Urinary macrophage contents in IgAN with moderate-severe renal injury were significantly higher than those in mild renal injury group(P<0.05).Conclusion:Testing urinary macrophages by flowcytometry may provide usful information for evaluating the degree of renal injury in IgAN.
Keywords:macrophages   flowcytometry   IgA nephropathy
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