Abstract: | ![]() Synthesis of Vinca Alkaloids and Related Compounds, X: Preparation of Biologically Active Derivatives of Indolopyridonaphthyridine The reaction of enamine derivatives of type 1 with α-substituted acrylic esters and with α-chloro-acrylonitrile furnishes a pentacyclic system. Some of the new compounds show significant vasodilator activity. |