昂丹司琼联合地塞米松在预防腹腔镜胆囊切除术后恶心呕吐的临床观察

目的探讨昂丹司琼联合地塞米松预防腹腔镜胆囊切除术后恶心呕吐（PONV）的临床效果。方法将我院收治的120例择期行腹腔镜胆囊切除术的患者随机分为对照组、单用昂丹司琼组和昂丹司琼联合地塞米松组各40例。观察PONV发生情况及不良反应情况。结果昂丹司琼联合地塞米松组的术后PONV发生率明显低于对照组和单用昂丹司琼组，昂丹司琼联合地塞米松组与单用昂丹司琼组不良反应发生率差异无统计学意义。结论昂丹司琼联合地塞米松预防腹腔镜胆囊切除PONV优于单用昂丹司琼。

Ondansetron Combined with Dexamethasone in the Prevention of Nausea and Vomiting after Llaparoscopic Cholecystectomy A: Clinical Observation

Objective To investigate the effect of ondansetron combined with dexamethasone in controlling PONV after laparoscopic cholecystectomy. Methods All of 120 patients treated with elective laparoscopic cholecystectomy by our hospital, were randomly divided into control group, ondansetron group and the ondansetron with dexamethasone group, 40 patients in every group, the occurrence of PONV and adverse reactions was observed. Results The occurrence of PONV in the ondansetron with dexamethasone group was lower than the control group and the ondansetron group ,but there were no statistical difference in the occurrence of adverse reactions among Ondansetron with dexamethasone and the ondansetron groups.Conclusion Ondansetron with dexamethasone have better effect in controlling PONV after laparoscopic cholecystectomy than ondansetron alone.