舌下免疫治疗在过敏性鼻炎中的应用效果

目的探讨舌下抗原特异性免疫在过敏性鼻炎中的应用效果。方法过敏性鼻炎患者120例，随机分为观察组与对照组各60例，对照组予对症治疗，观察组在此基础上加舌下免疫治疗。对比两组疗效评价观察组安全性。结果观察组总有效率显著高于对照组（P〈0．05）；两组AR评分及用药评分均较前显著改善（P〈0．05），治疗后观察组显著低于对照组（P〈0．05）；患者疗效自我评价显示，观察组总有效率显著高于对照组（P〈0．05）；治疗后嗜酸细胞计数呈下降趋势；观察组无严重不良反应出现。结论SLIT治疗AR疗效肯定，不良反应少，可达到根治目的。

The Effect of the Sublingual Immunotherapy Application on Allergic Rhinitis

Objective To disscuss the effect of sublingual immunotherapy on allergic rhinitis. Methods All of 120 patients with AR were randomly divided into two groups, patients in the control group were given symptomatic treatment, observation group was given symptomatic treatment and sublingual immunotherapy. Results The total effective rate in the observation group was significantly higher than control group （ P 〈 0.05 ） ; The symptom score and drug using score were improved significantly after treatment in both groups （ P 〈 0.05 ）, the observation group was significantly lower than control group （P 〈 0.05 ） ; The self-assessment of effcacy in observation group was significantly higher than control group （P 〈 0.05 ）. EOS account was reduced after treatment. There was no serious adverse reactions. Conclusion SLIT is effective and safty on patients with AR.