|
|||||
|
|
| 雌激素与活性氧 | |
| 引用本文： | 安尚玉,霍洪亮. 雌激素与活性氧[J]. 中国心血管杂志, 2007, 12(6): 472-473 |
| 作者姓名： | 安尚玉 霍洪亮 |
| 作者单位： | 东北师范大学生命科学学院,吉林,长春,130024 |
| 摘 要： | 大量证据表明活性氧(ROS)对心脑血管疾病的发生和发展有重要影响。它可以直接氧化膜脂质和DNA,造成细胞氧化损伤和异常;同时还作为信使参与细胞各种生理和病理活动,例如调节基因表达和信号转导。近几年,雌激素对心脑血管疾病的保护作用越来越受到人们的重视,它主要参与细胞内的氧化应激反应,但在某些方面也存在争议。 |
| 关 键 词： | 雌激素 活性氧 调节 |
| 文章编号： | 1007-5410（2007）06-0472-02 |
| 收稿时间： | 2007-09-04 |
| 修稿时间： | 2007-09-30 |
Estrogen and reactive oxygen species |
|
| AN Shang-yu,HUO Hong-liang. Estrogen and reactive oxygen species[J]. Chinese Journal of Cardiovascular Medicine, 2007, 12(6): 472-473 | |
| Authors: | AN Shang-yu HUO Hong-liang |
| Abstract: | A number of evidences indicated reactive oxygen species(ROS) have an important impact on the pathogenesis of cardiovascular and cerebrovascular diseases.ROS can react directly with cellular lipids and DNA,causing cell oxidative damage and dysfunction;also involve in cellular physiological and pathological processes as a messenger,such as regulating gene expression and signal transduction.In recent years,the protective effects of estrogen on the cardiovascular and cerebrovascular diseases have attracted more and more attention.It is mainly involved in intracellular oxidative stress,but in some aspects there are controversial. |
| Keywords: | Estrogen Reactive oxygen species Regulation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |