| 甲状腺相关眼病患者生存质量的研究现状 |
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| 引用本文： | 许根贵,吴艺君,朱秀影,盛文.甲状腺相关眼病患者生存质量的研究现状[J].国际眼科纵览,2012,36(5):331-336. |
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| 作者姓名： | 许根贵 吴艺君 朱秀影 盛文 |
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| 作者单位： | 温州医学院附属眼视光医院, 浙江,325027 |
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| 摘 要： | 甲状腺相关眼病（thyroidassociatedophthalmopathy，TAO）是一种自身免疫性疾病，临床表现为眼球突出、眼睑退缩、复视、角膜及视神经损伤等。各国学者采用一般生存质量量表、视功能损害相关性量表和甲状腺相关眼病生存质量量表评估TAO患者的生存质量及各种干预方式对其生存质量的影响，发现TAO引起的外观改变及视功能损害影响了患者的工作和生活，患者的精神心理压力巨大，生存质量严重下降。激素冲击、放射疗法、眶减压术等各种干预方式能一定程度改善患者生存质量，但效果不甚满意。开发适合TAO生存质量的评估体系及研究改善生存质量的手段是目前的研究热点和重点。（国际眼科纵览，2012，36：331—336）
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| 关 键 词： | 甲状腺相关眼病 生存质量 |
Health related quality of life in patients with thyroid associated ophthalmopathy |
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| XU Gen-gui
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WU Yi-jun
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ZHU Xiu-ying
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SHENG Wen.Health related quality of life in patients with thyroid associated ophthalmopathy[J].International Review of Opthalmology,2012,36(5):331-336. |
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| Authors: | XU Gen-gui WU Yi-jun ZHU Xiu-ying SHENG Wen |
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| Institution: | . Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou 325027, China |
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| Abstract: | Thyroid associated ophthalmopathy （TAO） is an autoimmune disease causing proptosis, eyelid retraction, motility disorders with diplopia, corneal damage, compressed optic nerve and so on. Re- searchers found that physical discomfort, facial disfigurement and impaired visual function caused by TAO have a negative impact on patients＇ employment, daily life, psychosocial function and their quality of life （ QOL）, using general health-related QOL questionnaires, vision-specific questionnaires and disease-specific QOL questionnaires. Intervening measures, including surgery, intravenous methylprednisolone, orbital ra- diotherapy and so on, could improve patients QOL, but not satisfying. In this review, we assess the evi- dence of the impact on patients＇ QOL, improving means and the social care of TAO. （Int Rev Ophthalmol, 2012, 36： 331-336） |
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| Keywords: | thyroid associated ophthalmopathy quality of life |
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