CRP与LDH的检测在结核性与癌性胸腔积液中的应用

目的 :探讨胸水C反应蛋白 (CRP)、乳酸脱氢酶 (LDH)测定及胸水 /血LDH的比值 ,对鉴别结核性和癌性胸腔积液的临床意义。方法 :检测 33例结核性胸腔积液病人和 2 1例癌性胸腔积液病人的胸水CRP、LDH及血LDH。结果 :结核性胸腔积液CRP水平明显高于癌性胸腔积液CRP值 (分别为 14 .2 4± 7.5 3,7.70± 4 .4 6 ,P <0 .0 5 ) ,结核性胸腔积液及癌性胸腔积液LDH及胸水 /血LDH比值比较差异均无显著性 (P >0 .0 5 )。结论 :CRP浓度测定是临床上常用的快速、实用的检测方法 ,对鉴别结核性及癌性胸腔积液有临床诊断价值。

Diagnostic Value of CRP and LDH in Tuberculous and Malignant Effusions

Objective To asses whether C-reactive protein (CRP) and lactate dehydrogenase (LDH) in pleural fluid and the ratio of pleural fluid to serum LDH were sensitive makers for distinguishing tuberculous and malignant effusion. Methods Pleural effusion HS-CRP, LDH and serum LDH were determined in 33 patients with tuberculous effusion and 21 patients with malignant effusion. Results CRP levels were (14.24±7.53)mg/L in tuberculous effusion and 7.70±4.46mg/l in malignant effusion, with a significant difference (P<0.05). Pleural fluid and serum LDH and their ratio were not different in the two kinds of effusion (P>0.05). Conclusion CPR determination is a rapid and practical method, it is valuable in differentiating tubersulos effusion from malignant effusion.