| 心脑通口服液质量控制方法研究 |
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| 引用本文： | 朱捷,吴新安.心脑通口服液质量控制方法研究[J].安徽医药,2012,16(2):175-177. |
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| 作者姓名： | 朱捷 吴新安 |
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| 作者单位： | 中国人民解放军第105医院药剂科,安徽,合肥,230031;中国人民解放军第105医院药剂科,安徽,合肥,230031 |
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| 基金项目： | 南京军区"122"工程培养项目，南京军区创新基金项目，安徽省卫生厅临床科研项目 |
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| 摘 要： | 目的建立心脑通口服液的质量控制方法。方法采用薄层色谱法对石菖蒲、泽泻、鸡血藤、延胡索进行定性鉴别;以乙腈-水(35∶65)为流动相,以283 nm为检测波长。结果黄芪苷的量在2.68～13.40μg范围内呈良好的线性关系(r=0.9996),回归方程为A=1.6579C+4.7705。精密度试验RSD为1.27%,该方法平均回收率为96.31%,RSD=1.08%。结论该方法对心脑通口服液质量可控。
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| 关 键 词： | 心脑通口服液 质量控制 |
Quality control on xinnaotong oral liquid |
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| ZHU Jie,WU Xin-an.Quality control on xinnaotong oral liquid[J].Anhui Medical and Pharmaceutical Journal,2012,16(2):175-177. |
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| Authors: | ZHU Jie WU Xin-an |
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| Institution: | (Department of Pharmacy,105 Hospital of PLA,Hefei 230031,China) |
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| Abstract: | Objective To develop a method of quality control of xinnaotong oral liquid.Methods Acorus gramineus,alisma orientalis,canlis spatholobi,and corydalis tuber were identified by TLC.The content of Baicalin was detected by HPLC（UV scan at wavelength 283nm,CH3CN∶ H2O（35∶ 65）as mobile phase）.Results Baicalin curvers were linear between 2.68 and 13.40 μg（r= 0.9996）.The mean recovery was 96.31%,and the RSD was 1.08%.Conclusion The method is sensitive and simpler. |
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| Keywords: | xinnaotong oral liquid quality control |
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