The prevalence and distribution of white-matter changes on different MRI pulse sequences in a post-stroke cohort |
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| Authors: | R. Mäntylä H. J. Aronen O. Salonen M. Korpelainen T. Peltonen C.-G. Standertskjöld-Nordenstam T. Erkinjuntti |
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| Affiliation: | (1) Department of Radiology, University of Helsinki, Haartmaninkatu 4, FIN-00290 Helsinki, Finland Tel.: + 358-9-4717 2479, Fax: + 358-9-4717 44 04, e-mail: riitta.mantyla@helsinki.fi, FI;(2) Department of Clinical Neurosciences, Memory Research Unit, Helsinki University Central Hospital, Helsinki, Finland, FI |
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| Abstract: | No uniform criteria currently exist for rating white-matter (WM) high-signal foci on MRI. Ratings are based on descriptive terms, different pulse sequences and different WM areas. Reports on the prevalence and clinical correlates of high-signal foci have been contradictory. We wanted to examine the contribution of the pulse sequence and WM area on rating WM changes. We analysed WM changes separately on T2-, protondensity (PD)- and T1-weighted images in periventricular, subcortical, watershed area and deep WM. The difference between T2- and PD-weighted images was significant for frontal caps, counting small foci or analysing subcortical changes. T1-weighted images showed significantly less change, but the number of foci detected was greater than previously thought. The prevalence of WM high-signal foci was greatest in the watershed zone and smallest in the subcortical area. There was a significant correlation between foci in different areas. |
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| Keywords: | Magnetic resonance imaging Ischaemia cerebral White matter |
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