支气管哮喘急性发作期雾化吸入治疗

目的观察雾化吸入布地奈德和特布他林对门诊轻、中急性发作期支气管哮喘患者的疗效。方法48例急性发作期支气管哮喘患者随机分为治疗组（26例）和对照组（22例）。治疗组每天雾化吸入布地奈德和特布他林雾化液7d，7d后吸入布地奈德气雾剂；对照组吸入布地夺德气雾剂和沙丁胺醇气雾剂（分别增加2次的剂量）；均于治疗前和治疗后第3、7和14d给予症状评分。结果治疗组治疗后第3、7d症状评分较对照组明显降低，但第14d两组无明显差异。结论雾化吸入布地奈德和特布他林起效快，可为门诊轻、中度急性发作期哮喘的首选给药方法。

Effects of Nebulized Budesonide Combined with Terbutaline in Patients with Bronchial Asthma of Acute Attack

Objective To observe the effect of nebulized budesonide combined with terbutaline in patients with bronchial asthma of acute attack in out-patient. Methods 48 light and moderate patients sufferd from acute attack of bronchial asthma were divided randomly into two groups(26 cases in therapy group and 22 cases in control group).The patient in therapy group inhaled nebulized budesonide and terbutaline at first,7days later,inhaled budesonide aerosol;and the patient in control used budesonide aerosol salbuterol aerosol(increasing 2 times dosage respectively).Before and after therapy 3~(rd),7~(th)and 14~(th)day,the symptom was scored.Results The symptom score in the therapy group were lower than those in control at the 3~(rd) and 7~(th) day,but no difference at 14~(th) day.Conclusion The effect of nebulizing budesonde and terbutaline is quick,which is the first step for acute attack of light and moderate bronchial asthma.