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孟鲁斯特辅助治疗小儿咳嗽变异性哮喘64例疗效观察
引用本文:邹嵘,邓少洁. 孟鲁斯特辅助治疗小儿咳嗽变异性哮喘64例疗效观察[J]. 北方药学, 2011, 8(5): 17-18
作者姓名:邹嵘  邓少洁
作者单位:南方医科大学附属深圳市妇幼保健院药剂科,深圳,518028;南方医科大学附属深圳市妇幼保健院药剂科,深圳,518028
摘    要:目的:观察孟鲁斯特辅助治疗儿童咳嗽变异性哮喘的临床效果。方法:采用随机分组,对128例咳嗽变异性哮喘患儿按照1:1的比例随机分为治疗组和对照组,其中对照组64例,予舒喘宁、酮替芬口服及普米克雾化吸入。治疗组64例,在对照组治疗的基础上,加用孟鲁斯特口服。分析治疗后两组咳嗽症状的改善情况。结果:治疗组疗效明显好于对照组,两组有统计学意义(P〈0.05)。结论:孟鲁斯特辅助治疗儿童咳嗽变异性哮喘疗效好,副作用少,值得推广。

关 键 词:孟鲁斯特  咳嗽变异性哮喘  小儿

Therapeutic efficacy of montelukast on children cough variant asthma.
Zou rong,Deng Shaojie. Therapeutic efficacy of montelukast on children cough variant asthma.[J]. BEIFANG YAOXUE, 2011, 8(5): 17-18
Authors:Zou rong  Deng Shaojie
Affiliation:(Department of Pharmacy,Affiliated Shenzhen Maternity ﹠ Child Healthcare Hospital,Southern Medical University. Shenzhen 518028,China)
Abstract:Objective:To assess the efficacy of montelukast on cough variant asthma(CVA) .Methods:128 children with CVA in clinic from Jun 2010 to Dec 2010 were randomly divided into two groups in the ratio of 1:1:objective group(n=64) and control group(n=64) .All the children of two groups took ketotifen and salbutamol and inhaled Pulmicort(Budesonide) ,while those of objective group additionally took montelukast;The remission of cough was recorded. Results:The effective rate of objective group was higher than that of the control group;A significant difference existed between the two groups(P 0.05) .Conclusion:The montelukast is effective for CVA,and has a little by-effect. It is worthy of being widely used.
Keywords:Montelukast Cough variant asthma(CVA) Children
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