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| 超声二维斑点追踪显像评价兔左心室局部心肌梗死后心肌舒缩功能 | |
| 引用本文： | 高晓丽,曾倩倩,穆玉明,曹桂秋,史琪,吴治胜. 超声二维斑点追踪显像评价兔左心室局部心肌梗死后心肌舒缩功能[J]. 新疆医科大学学报, 2011, 34(10) |
| 作者姓名： | 高晓丽 曾倩倩 穆玉明 曹桂秋 史琪 吴治胜 |
| 作者单位： | 1. 新疆医科大学第五附属医院超声诊断科,乌鲁木齐,830011 2. 新疆医科大学第一附属医院超声医学中心心脏超声科,乌鲁木齐,830011 |
| 摘 要： | 目的 应用超声斑点追踪技术(STI)研究兔左心室局部心肌梗死后心肌收缩及舒张功能.方法 健康新西兰兔随机分为正常对照组(假开胸组)和急性心肌梗死(AMI)组(结扎左冠状动脉前降支,造成左心室前壁心肌梗死),于实验后3 d分别采集两组动物左心室短轴二尖瓣口、乳头肌、心尖水平动态二维灰阶图像;应用STI技术分析左心室不同水平各节段心内膜下心肌径向应变率(SrR)、周向应变率(SrC)、旋转率(RotR)及扭转角度(Rot),并同步记录左心室压力指标.结果 (1) 与正常对照组比较,AMI组,左心室舒张末期压,左室射血分数(LVEF)、左心室短轴缩短率(LVFS)、左心室压力最大上升和下降速度(Ldp/dtmax)明显降低,左心室舒张末期内径(LVEDd)、左心室舒张末期压(LVEDP)明显升高,差异有统计学意义(P<0.05).(2) AMI组与正常对照组比较,AMI组局部梗死段SrR、SrC、RotR及Rot均下降.(3) AMI组梗死节段在3个水平间的SrR、SrC及RotR差异无统计学意义,规律消失.(4) STI所测得收缩期指标与dp/dtmax具有正相关(r=5.67,P<0.05),舒张期指标与LVEDP具有负相关(r=-5.06,P<0.05).结论 左心室扭转功能与LVdp/dtmax的相关性最强,左心室下壁对前壁心肌梗死的代偿作用最明显. |
| 关 键 词： | 超声心动图描记术 心肌梗死 斑点追踪成像 |
Assessment of left ventricular regional myocardial systolic function of rabbits with acute myocardial infarction by speckle tracking imaging |
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| GAO Xiao-li,ZENG Qian-qian,MU Yu-ming,CAO Gui-qiu,SHI Qi,WU Zhi-sheng. Assessment of left ventricular regional myocardial systolic function of rabbits with acute myocardial infarction by speckle tracking imaging[J]. Journal of Xinjiang Medical University, 2011, 34(10) | |
| Authors: | GAO Xiao-li ZENG Qian-qian MU Yu-ming CAO Gui-qiu SHI Qi WU Zhi-sheng |
| Affiliation: | GAO Xiao-li1,ZENG Qian-qian2,MU Yu-ming2,CAO Gui-qiu1,SHI Qi2,WU Zhi-sheng2(1Department of Echocardiography,Fifth Affiliated Hospital,2Department of Echocardiography,The First Affiliated Hospital,Xinjiang Medical University,Urumqi 830011,China) |
| Abstract: | Objective To assess the left ventricular regional myocardial systolic and diastolic function of rabbits with acute myocardial infarction(AMI) by 2-dimensional ultrasound speckle-tracking imaging.Methods Twenty-four healthy rabbits were randomly divided into two groups: group of sham-operated,group of AMI(induced by ligation of left anterior descending coronary artery).3 d after AMI,two-dimensional strain images were acquired from LV short-axis view(at the levels of mitral annulus,muscle papillary and apex),... |
| Keywords: | myocardial infarction myocardial systolic function speckle tracking imaging |
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