| 铬的安全性与毒理学研究进展 |
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| 引用本文： | 蒋与刚,刘静,庞伟.铬的安全性与毒理学研究进展[J].国外医学：医学地理分册,2006,27(3):97-99. |
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| 作者姓名： | 蒋与刚 刘静 庞伟 |
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| 作者单位： | 1. 军事医学科学院卫生学环境医学研究所,天津,300050
2. 四川大学华西医学中心,四川,成都,610041 |
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| 摘 要： | 由于铬缺乏与2型糖尿病、心血管疾病以及神经系统紊乱等疾病有关,而适量补铬可改善葡萄糖耐量、预防动脉粥样硬化,并增强机体免疫功能。因此,铬作为营养强化剂的安全性研究备受关注。动物实验和人体研究对摄入吡啶甲酸铬及其他三价铬的安全性进行了评价。从非致癌性毒性、潜在致癌性以及生物蓄积性等方面对该领域的研究进展作一综述。
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| 关 键 词： | 铬 安全性 毒理学 |
| 文章编号： | 1001-8883(2006)03-0097-03 |
| 收稿时间： | 2006-01-04 |
| 修稿时间： | 2006年1月4日 |
Advances in the safety of chromium |
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| Jiang Yu-gang,Liu Jing,Pang Wei.Advances in the safety of chromium[J].Foreign Medical Sciences(Section of Medgeography),2006,27(3):97-99. |
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| Authors: | Jiang Yu-gang Liu Jing Pang Wei |
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| Institution: | 1.Institute of Hygiene and Environmental Medicine of Academy Military Medical Science,Tianjin 300050; 2. Huaxi School of Public Health, Sichuan University,Chengdu 610041 China |
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| Abstract: | Trivalent chromium deficiency has been associated with such diseases as type 2 diabetes,cardiovascular disease,and nervous system disorders.Whlie improvement of glucose intolerance,prevention of atherosclerosis,and enhancement of immune function is observed after chromium supplementation.Hence,the study of safety of chromium tripicolinate for addition to foods as a nutrient supplement is needed.In order to evaluate the safety of chromium tripicolinate,the studies examined effects in animals or human clinical trials.In this article,we review the key studies that evaluated the non-carcinogenic toxicity,the potential carcinogenicity,and the bioaccumulation of chromium tripicolinate,as well as other trivalent chromium compounds. |
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| Keywords: | chromium safety toxicity |
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