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烟酒茶嗜好因素与中国女性乳癌关系的Meta分析
引用本文:王萍玉,谢书阳,张帅. 烟酒茶嗜好因素与中国女性乳癌关系的Meta分析[J]. 康复与疗养杂志, 2010, 0(1): 3-7
作者姓名:王萍玉  谢书阳  张帅
作者单位:[1]滨州医学院卫生学教研室,山东烟台264003 [2]滨州医学院生物化学与分子生物学研究室,山东烟台264003
基金项目:山东省高等学校科技计划项目(J09LF11).
摘    要:目的综合分析评价烟酒茶嗜好因素与中国女性乳癌的关系,探索乳癌的危险因素。方法收集我国1994-2008年间有关烟酒茶嗜好因素和乳癌的病例对照研究文献,利用Meta分析的方法对检索出的符合要求的文献进行再分析,定量综合评价烟酒茶嗜好与乳癌的关系。结果纳入本次Meta分析的文献共8篇,乳癌病例共1580例,对照者共2399例。吸烟合并OR=1.89(95%CI:1.27~2.81),饮酒合并OR=0.73(95%CI:0.53~0.99),饮茶合并OR=0.84(95%CI:0.70~1.02)。结论吸烟尤其是被动吸烟是乳癌发生的危险因素,倡导全民戒烟,减少乳癌的发生;饮酒饮茶与乳癌关系有待进一步研究。

关 键 词:乳腺肿瘤  病例对照研究  危险因素  Meta分析

Meta-ANALYSIS OF POSSIBLE RELATIONSHIP BETWEEN HOBBIES OF SMOKING, ALCOHOL AND TEA WITH BREAST CANCER IN CHINESE WOMEN
WANG PING-YU,XIE SHU-YANG,ZHANG SHUAI. Meta-ANALYSIS OF POSSIBLE RELATIONSHIP BETWEEN HOBBIES OF SMOKING, ALCOHOL AND TEA WITH BREAST CANCER IN CHINESE WOMEN[J]. , 2010, 0(1): 3-7
Authors:WANG PING-YU  XIE SHU-YANG  ZHANG SHUAI
Affiliation:(Binzhou Medical College, Yantai 264003, China)
Abstract:Objective To analyze the association of hobbies of smoking, alcohol and tea with breast cancer and its risk factors in Chinese women. Methods Data of case-control studies on breast cancer in China from 1994 to 2008 were collected and analyzed synthetically by using Meta-analysis. Results Eight literatures met the criteria were enrolled in the Meta-analysis, in which, 1 580 cases were breast cancer and 2 399 controls. For smoking, summary odds ratio (OR) was 1.89, 95% confidence interval (1.27-2.81); for alcohol, OR:0.73,95% CI(0.53-0.99); and for tea, OR:0.84,95% CI(0. 70-1. 02). Conclusion Smoking, passive smoking in particular, significantly increases the risk of breast cancer, while alcohol and tea are to be investigated.
Keywords:breast neoplasms  case control studies  risk factors  meta-analysis
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