| 万拉法新与阿米替林治疗抑郁症临床对照研究 |
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| 引用本文： | 张凤桥,赵波,孝金萍,王泉英.万拉法新与阿米替林治疗抑郁症临床对照研究[J].山东精神医学,2004,17(1):19-20. |
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| 作者姓名： | 张凤桥 赵波 孝金萍 王泉英 |
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| 作者单位： | [1]山东省滨州市人民医院精神卫生中心,256613 [2]山东省滨州市复退军人医院,256613 |
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| 摘 要： | 目的进一步验证万拉法新治疗抑郁症的疗效及副作用。方法将符合CCMD-3抑郁症诊断标准的门诊及住院患者40例随机分为2组，分别给予万拉法新或阿米替林治疗，疗程6周。用HAMD量袁在用药前及用药后1、2、4、6周评定药物疗效；用TESS量表评定副反应。结果万拉法新与阿米替林疗效相当，但万拉法新起效快，副反应轻。结论万拉法新治疗抑郁症起效快，疗效好而安全。
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| 关 键 词： | 万拉法新 阿米替林 抑郁症 临床对照研究 副作用 抗抑郁药 |
| 文章编号： | 1009-7201(2004)-01-0019-02 |
| 修稿时间： | 2002年3月20日 |
A controlled study of venlafaxine and amitriptyline in the treatment of depression |
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| Zhang Fengqiao,Zhao Bo,Xiao Jinping,et al..A controlled study of venlafaxine and amitriptyline in the treatment of depression[J].Shangdong Archives of Psychiatry,2004,17(1):19-20. |
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| Authors: | Zhang Fengqiao Zhao Bo Xiao Jinping |
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| Institution: | Zhang Fengqiao,Zhao Bo,Xiao Jinping,et al.The Mental Health Center of Binzhou People's Hospital,Shandong 256613,China |
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| Abstract: | Objective To explore the efficacy and side effects of venlafaxine in the treatment of depression.Methods The forty out- or in- patients met with the criteria for depression of CCMD-3 were treated randomly with venlafaxine or amitriptyline for 6 weeks,and measured with HAMD and TESS before treatment and 1?2?4?6 weeks after treatment.Results The both drugs were similar in effecacy.Venlafaxine showed effects earlier and fewer side effects than amitriptyline.Conclusion Venlafaxine is effective and safe in the treatment of depression. |
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| Keywords: | Venlafaxine Amitriptyline Depression |
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