THE EFFECT OF PROPRANOLOL ON THYROID HORMONES AND OXYGEN CONSUMPTION IN THYROTOXICOSIS |
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| Authors: | J. SAUNDERS,SUSAN E. H. HALL,A. CROWTHER,P. H. SÖ NKSEN |
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| Affiliation: | Department of Medicine, St ThomasS Hospital Medical School, London |
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| Abstract: | ![]()
The possibility that propranolol may exert its beneficial actions in thyrotoxicosis by an effect on thyroid hormone concentrations has been investigated by measuring these and oxygen consumption in a group of thyrotoxic patients before and after treatment with propranolol. Following treatment a significant fall in plasma T3 concentration and oxygen consumption occurred and a direct correlation was found between these two variables. Propranolol may, therefore, exert some of its beneficial effects in thyrotoxicosis by an action on T3 metabolism. |
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