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人工周期准备子宫内膜进行复苏囊胚移植的影响因素分析
引用本文:高辉,孙正怡,邓成艳,郁琦,何方方. 人工周期准备子宫内膜进行复苏囊胚移植的影响因素分析[J]. 生殖医学杂志, 2008, 17(2): 85-89
作者姓名:高辉  孙正怡  邓成艳  郁琦  何方方
作者单位:中国医学科学院,北京协和医学院,北京协和医院妇产科,北京,100730
摘    要:
目的探讨采用人工周期准备子宫内膜进行复苏囊胚移植影响临床结局的相关因素。方法对2004年3月至2007年2月期间,采用人工周期准备子宫内膜的192个复苏囊胚移植周期进行回顾性分析。结果年龄及是否患有多囊卵巢综合征(PCOS)与移植后的妊娠结局相关(分别为P=0.027,OR值1.647及P=0.037,OR值0.437)。随年龄增加妊娠率和种植率呈下降趋势(≤30岁:61.4%和44.1%;31~34岁:53.8%和36.6%;≥35岁:39.0%和25.3%)。PCOS患者妊娠率和种植率分别为37.8%和25.0%,明显低于非PCOS患者(58.2%、42.5%)。戊酸雌二醇(E2V)起始剂量及用黄体酮前E2V的用药天数、总量与妊娠结局无关。结论年龄以及是否患有PCOS与妊娠结局相关,年轻的、非PCOS患者有较好的临床结局;并强调用药的个体化。

关 键 词:人工周期  囊胚移植  子宫内膜容受性  复苏囊胚
文章编号:1004-3845(2008)02-0085-05
修稿时间:2007-08-28

Analysis of the clinical factors for frozen-thawed blastocyst transfer in hormonally controlled cycles
GAO Hui,SUN Zheng-yi,DENG Cheng-yan,YU Qi,HE Fang-fang. Analysis of the clinical factors for frozen-thawed blastocyst transfer in hormonally controlled cycles[J]. Journal of Reproductive Medicine, 2008, 17(2): 85-89
Authors:GAO Hui  SUN Zheng-yi  DENG Cheng-yan  YU Qi  HE Fang-fang
Affiliation:GAO Hui,SUN Zheng-yi,DENG Cheng-yan,YU Qi,HE Fang-fang Department of Obstetrics & Gynecology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing100730
Abstract:
Objectives:To analyze how the clinical factors affect the outcomes of frozen-thawed blastocyst transfer in hormonally controlled cycles without prior GnRH agonist suppression.Methods:This retrospective study included 192 frozen-thawed blastocyst transfer cycles(FET,338 blastocysts involved).These cycles used estradiol valerate and progesterone preparations without the concomitant use of GnRHa,performed from March 2004 to February 2007 in our reproductive center.The relationship was analyzed with logistic re...
Keywords:Hormonally controlled cycle  Blastocyst transfer  Endometrial receptivity  Frozen-thawed blastocyst  
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