腺性膀胱炎的研究进展

目前,腺性膀胱炎的病因及生物学意义尚未完全明了,但通过研究发现主要是与感染、结石、梗阻、异物、留置导尿管等慢性刺激长期作用,黏膜上皮增生形成Brunn巢有一定关系,另外与ras等基因蛋白和细胞角蛋白19表达异常和人类乳头状瘤病毒感染有关,且具有癌变倾向。其临床表现无显著的特征,诊断依据病理活组织检查,大部分含有Brunn巢。现有的治疗方法较多,包括手术治疗、药物灌注治疗、放射治疗和生物治疗等,多数采用综合治疗,但去除病因的治疗尤为重要。

The Advances of Research in Cystitis Glandularis

At present,the etiopathogenisis and biological significance of cystitis glandularis is unclear to some extent.But some investigations show that cystitis glandularis is related to the long-term and chronical stimulus of infection,calculus,obstruction,foreign object,retention type catheter,and to the Brunn's nests resulting from the mucosa epithelial proliferation.Other studies prove that it is closely connected with the abnormal expression of ras gene-proteinum and cytokeratin-19,and with the infection of hu...