Radiotherapy for early glottic cancer and salvage surgery after recurrence |
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| Authors: | Paulo Pontes Osíris de Oliveira Camponês do Brasil Francisco de Souza Amorim Filho Bruno Teixeira de Moraes Antonio Pontes José Caporrino Neto |
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| Affiliation: | 1. Full Professor - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM;2. PhD in Sciences; Professor - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM;3. Head and Neck Surgeon; PhD in Sciences - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM;4. Otorhinolaryngologist; MSc student - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM;5. Otorhinolaryngologist; MSc student - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM;6. PhD in Sciences; Assistant Physician - Department of Otorhinolaryngology and Head and Neck Surgery of the Federal University of São Paulo, UNIFESP-EPM |
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| Abstract: | ![]()
Early glottic cancer can be effectively treated with radiation or surgery, but recurrence is a possibility when using any of the treatment modalities.AimTo assess the outcome of radiotherapy as initial treatment in the control of squamous cell carcinoma of vocal cord (T1) and the effectiveness of salvage surgery (endoscopic or open) after treatment failure.Materials and MethodsA retrospective study was based on the analysis of medical records from 43 patients with T1 squamous cell carcinoma of the glottis, radiotherapy as initial treatment and follow-up period of five years.ResultsThe rate of recurrence after radiotherapy was 30.2% of the cases, mean diagnosis interval was 29.5 months. As an option for salvage treatment, patients underwent open partial laryngectomy or endoscopic surgery with control rates of 77.7% and 25% respectively.ConclusionOur cases showed high rates of recurrence after radiotherapy and open partial laryngectomy was more effective for the salvage surgery. |
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| Keywords: | laryngeal neoplasms laryngectomy neoplasm recurrence local radiotherapy salvage therapy |
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