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| PCR法检测宫颈癌细胞中人乳头瘤病毒 | |
| 引用本文： | 熊华淇,邹桂华. PCR法检测宫颈癌细胞中人乳头瘤病毒[J]. 江西医学院学报, 1996, 0(3) |
| 作者姓名： | 熊华淇 邹桂华 |
| 作者单位： | Department of Pathology，Jiangxi Medical college，Nanchang 330006 |
| 摘 要： | 采用ＰＣＲ（聚合酶链反应）技术对宫颈癌细胞中ＨＰＶ（人乳头瘤病毒）和ＨＰＶ１６、１８型的感染状况分别进行了研究。在新鲜组织中，宫颈癌细胞内ＨＰＶ和ＨＰＶ１６、１８型的感染率分别达８０％和７５％。但石蜡标本中ＨＰＶ和ＨＰＶ１６、１８型的感染率则为３３．３％和２６．７％。说明宫颈癌细胞中ＨＰＶ的感染率极高，且主要系ＨＰＶ１６、１８型的感染。ＰＣＲ技术检测宫颈癌细胞中的ＨＰＶ方法简便快速，灵敏度高。可广泛用于流行病学调查和高危致癌ＨＰＶ感染妇女的追踪观察。对宫颈癌的早期发现和早期诊断有重要意义 |
| 关 键 词： | 子宫颈肿瘤 癌 乳头状瘤 病毒 聚合酶链反应 |
Detection of Human Papillomavirus in Cervical Carcinomas with PCR Technique |
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| Xiong Huaqi Zou Guihua. Detection of Human Papillomavirus in Cervical Carcinomas with PCR Technique[J]. Acta Academiae Medicinae Jiangxi, 1996, 0(3) | |
| Authors: | Xiong Huaqi Zou Guihua |
| Abstract: | Human papillomavirus(HPV) and type 16.18 of HPV DNA in human cervical carcinoma have been detected with polymerase chain reaction.In fresh specimens the infection rate of HPV and HPV16.18 were 80% and 75% separately.However in paraffin embedded specimens the infection rate of HPV and HPV16.18 were 33 3% and 26 7% respectively.The results shows the infection rate of HPV in human cervical carcinoma is very high.Most of them were HPV 16.18 infection.PCR technique is a convenient and sensitive method in detecting HPV infection in human cervical carcinoma.It can be used in epidemic investigation and early findings of cervical carcinoma. |
| Keywords: | cervix neoplasms carcinomas papillomaviruses polymerase chain reaction |
| 本文献已被 CNKI 等数据库收录！ | |