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罗红霉素干预治疗铜绿假单胞菌肺部感染的临床研究
引用本文:徐西琳,毛梅,陈真真,傅祖红,熊盛道. 罗红霉素干预治疗铜绿假单胞菌肺部感染的临床研究[J]. 中国药师, 2011, 14(2): 239-241
作者姓名:徐西琳  毛梅  陈真真  傅祖红  熊盛道
作者单位:1. 华中科技大学同济医学院附属同济医院呼吸内科,武汉,430030
2. 广州军区武汉总医院呼吸内科
摘    要:目的:探讨罗红霉素干预治疗铜绿假单胞菌肺部感染的疗效。方法:64例铜绿假单胞菌肺部感染患者随机分为两组,试验组口服罗红霉素0.15 g,bid,同时静滴一种药敏试验对铜绿假单胞菌敏感的抗菌药;对照组仅给予一种药敏试验对铜绿假单胞菌敏感的抗菌药静滴。两组疗程均为2周。结果:试验组的临床痊愈率、有效率显著高于对照组,症状、体征好转及中性粒细胞比例恢复正常的平均天数也明显低于对照组,细菌清除率明显高于对照组(P均<0.05)。结论:罗红霉素联合敏感抗菌药治疗铜绿假单胞菌肺部感染的疗效优于单用敏感抗菌药。

关 键 词:罗红霉素  铜绿假单胞菌  干预治疗

Clinical Study on Intervention Treatment for Pulmonary Infection by Pseudomonas Aeruginosa with Roxithromycin
Xu Xilin,Mao Mei,Chen Zhenzhen,Fu Zuhong,Xiong Shengdao. Clinical Study on Intervention Treatment for Pulmonary Infection by Pseudomonas Aeruginosa with Roxithromycin[J]. China Pharmacist, 2011, 14(2): 239-241
Authors:Xu Xilin  Mao Mei  Chen Zhenzhen  Fu Zuhong  Xiong Shengdao
Affiliation:Xu Xilin~1,Mao Mei~2,Chen Zhenzhen~2,Fu Zuhong~2,Xiong Shengdao~1(1.Department of Respiratory Medicine,Affiliated Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China,2.Department of Respiratory Medicine,Wuhan General Hospital of Guangzhou Military Command)
Abstract:Objective:To research the intervention treatment of roxithromycin for pulmonary infection by Pseudomonas aeruginosa. Method:Sixty-four patients with pulmonary infection by Pseudomonas aeruginosa were divided into experimental group and control group.The experimental group administrated roxithromycin 150mg twice a day orally combined with i.d one kind of antibiotic sensitive to Pseudomonas aeruginosa.The control group was only treated with the antibiotic sensitive to Pseudomonas aeruginosa.The course of trea...
Keywords:Roxithromycin  Pseudomonas aeruginose  Intervention treatment  
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