皮肤科药疹患者皮疹特点及药学监护分析

目的通过分析我院皮肤科住院药疹患者的病历资料,了解住院患者药疹的情况和重症药疹的皮疹特点,并对此进行药学监护分析。方法回顾性分析2009年7～12月我院皮肤科收治确诊药疹的患者42例。结果药疹致敏药物主要构成为抗生素类(50.00%),解热镇痛类(19.05%),生物制品类(4.76%),抗痛风类(2.38%);药疹疹型主要构成为红斑疹型(69.05%),斑丘疹型(14.29%),猩红热样、麻疹样、多形红斑样荨麻疹(共占7.14%),固定型疹(4.76%)及重症药疹(4.76%)。结论抗生素类药物是药疹的主要致敏药物,抗癫痫类药是重症药疹的主要致敏药物,故建议临床医务人员应详细询问患者用药史,及时停用可疑致敏药物,并加强药学监护。

Clinical Analysis and Pharmaceutical Care of Inpatients with Drug Eruption

Objective To investigate the clinical feature and pharmaceutical care of inpatients with drug eruption,especially those with severe drug eruption.Methods A retrospective analysis was carried out on the clinical date on all patients(42cases) with drug eruption from July 2009 to December 2009.Results The composition of causative drugs was an-timicrobial drugs(50.00%),antipyretic analgesic(19.05%),biological products(4.76%),antigout drugs(2.38%).The com-position of clinical manifestation was rash erythematous(...