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Shaping macrophages function and innate immunity by bile acids: Mechanisms and implication in cholestatic liver diseases
Affiliation:1. Centre de référence des maladies inflammatoires des voies biliaire, Service d’hépatologie et Centre de transplantation hépatique, AP–HP, Hôpital Saint-Antoine, 75571 Paris cedex 12, France;2. France Sorbonne universités, UPMC université Paris 06, 75006 Paris, France;1. Department of Endocrinology and Metabolism, Hebei General Hospital, Shijiazhuang, Hebei 050051, China;2. Research Division, Joslin Diabetes Center, and Harvard Medical School, Boston, MA 02215, USA;1. European Genomic Institute for Diabetes (EGID), FR 3508, 59000 Lille, France;2. Université Lille 2, 59000 Lille, France;3. Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1011, 59000 Lille, France;4. Institut Pasteur de Lille, 59000 Lille, France;1. Department of Microbiology and Immunology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA;2. McGuire VA Medical Center, Richmond, VA 23249, USA;1. University of Perugia Medical School, Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Via L. Severi 1-06132, Perugia, Italy;2. Azienda Ospedaliera di Perugia, Via L. Severi 1-06132, Perugia, Italy;1. Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia;2. Clinical Centre of Vojvodina, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1, 21000 Novi Sad, Serbia;3. School of Pharmacy, Curtin University, Kent Street Bentley WA 6102, 6845 Perth, Australia
Abstract:
Keywords:BEC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0010"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  biliary epthelial cells  CA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0020"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cholic acid  CBP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0030"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  CREB-binding protein  CDCA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  chenodeoxycholic acid  DCA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  deoxycholic acid  FXR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  farnesoid X receptor  GR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  glucocorticoid receptor  ISG"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  IFN-stimulated gene  PBC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  primary biliary cirrhosis  PKI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  PKA inhibitor  PSC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  primary slerosing cholangitis  SP1R2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  sphingosine-1-phosphate receptor 2  TGR5"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0130"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  G-protein-coupled bile acid receptor  TLC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0140"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  taurolithocholic acid  TLR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0150"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Toll/IL-1R (TIR) domain-containing adapter-inducing IFN-β  TUDC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kw0160"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  tauroursodeoxycholic acid
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