喉透明细胞癌1例报道并文献复习

目的 分析喉透明细胞癌的临床及病理组织学特征。方法 运用光镜、电镜及免疫组化技术，研究报道1例喉透明细胞癌，同时复习相关文献。结果 喉透明细胞癌癌细胞胞质透明，异型性明显，免疫组化上皮抗原标记( )，电镜观察发现肿瘤细胞有腺样结构形成。结论 喉透明细胞癌是一种分化较低的腺源性恶性肿瘤，具有高度侵袭性的生物学特征，应与其他部位转移的透明细胞癌鉴别。

Clear cell carcinoma of larynx: a case report and review of literature

Objective To analyze the clinical and pathologic featuers of clear cell carcinoma of the larynx. Methods The case of clear cell carcinoma of larynx was studied by using histochemistry, immunohistochemistry and electron microscopy, with review of the relevent literature. Results Microscopially, the clear cell carcinoma of the larynx had vacuolated cytoplasm and highly atypical, bizarre cells. Immunohistochemically, the neoplastic elements were positive for the epithelial antibodies. Ultrastructural studies showed that the tumor cells had glandular differentiation. Conclusions Clear cell carcinoma of the larynx is a kind of adenoid malignant tumors with poorly differentiated elements, and it has highly invasive featuers. The differential diagnosis must be made from metastatic clear cell carcionma from other organs.