中晚期宫颈癌新辅助化疗方法的综合评价

近来相继有临床报道提出在手术、放疗之前行新辅助化疗,对局部晚期宫颈癌和具有不良预后因素的高危患者疗效良好。新辅助化疗的主要途径包括:手术或放疗前全身静脉化疗、动脉插管介入栓塞化疗和宫颈癌病灶局部注射化疗等。这三种途径各有优势,本文旨在对以上三种用药途径进行综合评价,以期选择最佳方案,进一步指导临床。

Evaluation of Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer

Recently many clinical reports have suggested that the neoadjuvant chemotherapy before operation or radiotherapy is effective on locally advanced cervical cancer and patients at high risk for poor prognostic factors, The chief approaches of neoadjuvant chemotherapy are systemic intravenous chemotherapy before operation or radiotherapy, uterine artery interventional chemotherapy and embolization, as well as local chemotherapy. The three methods have their own advantages. The paper makes a comprehensive evaluation of the three methods in order to choose the optimal scheme and further provide clinical guidance.