| 自体骨髓单个核细胞移植治疗糖尿病下肢血管病变疗效及其与血清肝细胞生长因子的关系 |
| |
| 引用本文： | 甘宇,于黎丽,李铁男,郑长虹. 自体骨髓单个核细胞移植治疗糖尿病下肢血管病变疗效及其与血清肝细胞生长因子的关系[J]. 中国实用内科杂志, 2010, 0(3) |
| |
| 作者姓名： | 甘宇 于黎丽 李铁男 郑长虹 |
| |
| 作者单位： | 沈阳市第七人民医院; |
| |
| 基金项目： | 沈阳市科技基金资助项目(1071194-9-00) |
| |
| 摘 要： | 目的探讨自体骨髓单个核细胞移植治疗糖尿病下肢血管病变的疗效及其与血清肝细胞生长因子(HGF)水平的关系。方法选择2006年6月至2009年6月沈阳市第七人民医院79例糖尿病下肢血管病变患者,分为常规治疗组(A组,40例,80条患肢)和自体骨髓单个核细胞移植治疗组(B组,39例,78条患肢),治疗6个月后对疗效及其与血清HGF关系进行评估。结果(1)B组治疗后1周肢体疼痛、患肢冷感、皮肤温度、血清HGF与B组治疗前及A组治疗后1周比较差异有统计学意义(P0.05),并与血清HGF存在相关性(P0.05)。(2)B组治疗后3个月、6个月各项临床观察指标与B组治疗前及A组治疗后相同时间点比较差异均有统计学意义(P0.05)。结论自体骨髓单个核细胞移植技术治疗糖尿病下肢血管病变可以提高疗效,不会导致由于血清HGF长期增高引起的副反应。
|
| 关 键 词： | 骨髓单个核细胞 移植 糖尿病 下肢血管病变 肝细胞生长因子 |
Therapeutic effect of autologous bone marrow mononuclear cell transplantation on diabetic lower extremity vascular disease and its relation with serum level of HGF |
| |
| GAN Yu,YU Li-li,LI Tie-nan,ZHENG Chang-hong. Therapeutic effect of autologous bone marrow mononuclear cell transplantation on diabetic lower extremity vascular disease and its relation with serum level of HGF[J]. Chinese Journal of Practical Internal Medicine, 2010, 0(3) |
| |
| Authors: | GAN Yu YU Li-li LI Tie-nan ZHENG Chang-hong |
| |
| Affiliation: | GAN Yu,YU Li-li,LI Tie-nan,ZHENG Chang-hong.The Seveth Hospital of Shenyang,Shenyang 110003,China |
| |
| Abstract: | Objective To probe therapeutic effect of autologous bone marrow mononuclear cell transplantation on diabetic lower extremity vascular disease and its association with serum level of HGF.Methods 79 diabetic lower extremity vascular disease cases was divided into regular treated group (group A):40 cases,80 affected limbs;autologous bone marrow mononuclear cell transplantation treated group (group B):39 cases,78 affected limbs.And the therapeutic effect as well as serum level of HGF was evaluated after 6-month... |
| |
| Keywords: | bone marrow mononuclear cell transplantation diabetes lower extremity vascular disease HGF |
| 本文献已被 CNKI 等数据库收录！ |
