Abstract: | The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Trial was a multicenter, randomized trial designed with the purpose of determining the clinical impact of immediate or deferred angioplasty on left ventricular function following successful myocardial reperfusion with tissue plasminogen activator (t-PA). Results from this trial indicate that immediate coronary angioplasty following successful thrombolysis, when coronary artery anatomy is suitable, offers no advantage over delayed elective angioplasty. The purpose of this article is to discuss and critically review the TAMI trial. Details of the trial will be discussed followed by a critique and implications for nursing. |