| 沙棘对高脂血清培养平滑肌细胞的保护作用 |
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| 引用本文： | 王宇,卢咏才,刘小青,郭肇铮,胡金红.沙棘对高脂血清培养平滑肌细胞的保护作用[J].中国中药杂志,1992,17(10):624-6, 601, inside back cover. |
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| 作者姓名： | 王宇 卢咏才 刘小青 郭肇铮 胡金红 |
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| 作者单位： | 北京中医学院 100029
(王宇，卢咏才，刘小青，郭肇铮)，北京中医学院 100029(胡金红) |
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| 摘 要： | 首次从亚细胞水平证实沙棘与维生素E相似,对高脂血清损伤的干滑肌细胞有如下的保护作用:1.降低细胞内脂质过氧化物含量;2.减轻细胞膜的损伤;3.保护细胞健康生长并促其增生。
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| 关 键 词： | 沙棘 平滑肌细胞 高脂血症 脂质过氧化 动脉粥样硬化 |
The Protective Effect of Hippophae rhamnoides L. on Hyperlipidemic Serum Cultured Smooth Muscle Cells in Vitro |
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| Wang Yu,Lu Yongcai,Liu Xiaoqing,Gou Zhaozhen and Hu Jinhong.The Protective Effect of Hippophae rhamnoides L. on Hyperlipidemic Serum Cultured Smooth Muscle Cells in Vitro[J].China Journal of Chinese Materia Medica,1992,17(10):624-6, 601, inside back cover. |
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| Authors: | Wang Yu Lu Yongcai Liu Xiaoqing Gou Zhaozhen and Hu Jinhong |
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| Institution: | Beijing College of Traditional Chinese Medicine 100029 |
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| Abstract: | The effect of Hippophae rhamnoides on hyperlipidemicrabbit sernm(HRS)cultured smooth muscle cells(SMC)was observed in comparison with vitamin E(VE).The results show that Hippophae rhamnoides, much like VE, is also a potent antioxidant. It strongly decreases the MDA content in HRS cultured SMC and protect the cells from the injury of lipid peroxidation, and thus keeps the SMC growing and proliferating healthily. The results implicats that Hippophae rhamnoides is an effective antioxidant, and one of the important mechanisms of Hippophae rhamnoides in anti-atherosclerosis reported recently may be closely related to the action of anti-lipid peroxidation. |
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| Keywords: | Hippophae rhamnoides smooth muscle cell atherosclerosis lipid peroxidation hyperlpidemia |
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