Liver transplant for relapsed undifferentiated embryonal sarcoma in a young child |
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| Authors: | Michael J. Kelly Laura Martin Maria Alonso Rachel A. Altura |
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| Affiliation: | aDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Hasbro Children's Hospital and The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA;bDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH 43205, USA;cDepartments of Surgery and Pediatrics, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA |
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| Abstract: | ![]()
Undifferentiated embryonal sarcoma of the liver is a rare hepatic malignancy of childhood with a historically poor prognosis. Recent improvements in outcomes have been reported in small numbers of cases with the use of combination therapy involving aggressive surgical resection and chemotherapy. Complete surgical resection is frequently difficult to achieve when the location of the tumor is along the margins of the major hepatic vessels (portal vein, hepatic vein, and hepatic artery). Here we report a case of undifferentiated embryonal sarcoma of the liver that recurred along surgical hepatic vein margins in a 9-year-old boy who subsequently underwent orthotopic liver transplantation from a cadaveric donor. The patient has been in continuous clinical remission for the last 5 years. |
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| Keywords: | Liver Sarcoma Transplant Child |
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