Vascular Risk Factors as Predictors of Sexual Function Following Coronary Artery Bypass Graft |
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| Authors: | Osama A. Mohamed Hamed A. Hamed Mohamed Farid Roaiah Tarek Helmy Ali Mahran Carol J. Bennett |
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| Affiliation: | 2. Andrology Department, Faculty of Medicine, Cairo University, Cairo, Egypt;;3. Cardiothoracic Department, Faculty of Medicine, Cairo University, Cairo, Egypt;;4. Andrology Department, Faculty of Medicine, Asyut University, Asyut, Egypt;;5. Urology, Greater Los Angeles VA Medical System, Los Angeles, CA, USA;;1. National Psychotrauma Centre for Children and Youth, University Medical Centre, Utrecht, The Netherlands;2. Department of Obstetrics and Gynaecology, University Medical Centre, Utrecht, The Netherlands;3. Department of Sexology and Psychosomatic Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands;1. Paediatric and Congenital Cardiology Department, M3C Regional Reference CHD Centre, CHU Montpellier, Montpellier, France;2. PhyMedExp, CNRS, INSERM, University of Montpellier, Montpellier, France;3. Paediatric Cardiology and Rehabilitation Centre, Institut-Saint-Pierre, Palavas, Les-Flots, France;4. Paediatric Cardiology Department, AP-HP, Necker-Enfants malades, M3C National Reference CHD Centre, Paris Descartes University, Sorbonne Paris Cite, Paris, France;5. Paediatric Cardiology Department, Children''s Hospital, M3C Regional Reference CHD Centre, University Hospital of Nancy, Vandoeuvre-les-Nancy, France;6. Department of Cardiology, M3C Regional Reference CHD Centre, CHU Grenoble, France;7. Mother and Children Hospital, CHU Limoges, France;8. CHD private medical office, Massy, France;9. Paris-Sud Faculty of Medicine, INSERM U999, Marie-Lannelongue Hospital, M3C National Reference CHD Centre, Paris-Sud University, Paris, Saclay, Le Plessis-Robinson, France;10. Cardiac Rehabilitation Centre, Hospital of Bligny, Bris-sous-Forge, France;11. Department of Cardiology, M3C Regional Reference CHD Centre, Gabriel Montpied University Hospital, Clermont-Ferrand, France;12. Paediatric Cardiology Unit, Children''s Hospital, M3C Regional Reference CHD Centre, CHU Toulouse, France;13. Paediatric and Adult Congenital Heart Disease Department, Hôpital Cardiologique du Haut-Lévêque, M3C National Reference CHD Centre, CHU de Bordeaux, Bordeaux, Pessac, France;14. Adult Congenital Heart Disease Unit, Department of Cardiology, European Hospital Georges Pompidou, M3C National Reference CHD Centre, Paris, France;15. Paediatric and Congenital Medico-Surgical Cardiology Department, M3C Regional Reference CHD Centre, AP-HM, La Timone University Hospital, Marseille, France;p. Cardiac Rehabilitation Centre, Beaumont-de-Lomagne, France;q. Department of Epidemiology and Biostatistics, CHU Montpellier, France;r. Leon Berard Hospital, Cardiac Rehabilitation Centre, Hyeres, France;s. Cardiac Rehabilitation Centre, Fontfroide Clinic, Montpellier, France;t. Cardiology Department, Caremeau University Hospital, Nimes, France;u. Laboratory of Medical Genetics, INSERM UMR 1251, Aix-Marseille University, Marseille, France;v. Department of Cardiology, Clinique Pasteur, Toulouse, France |
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| Abstract: | IntroductionA strong association between cardiovascular risk factors and erectile dysfunction (ED) was suggested. Coronary artery bypass grafting (CABG) is the gold standard for surgical myocardial revascularization.AimWe herein evaluate the impact of vascular risk factors on postoperative sexual functions in patients undergo CABG.Main Outcome MeasuresED severity by the International Index of Erectile Function (IIEF-5) and penile duplex study.MethodsThe present study included 100 patients who underwent CABG. The patients were evaluated by an abridged form of the IIEF-5 questionnaire, followed by CABG. Six months after surgery the erectile function of all patients was revaluated utilizing the IIEF-5.ResultsNumber of risk factors was significantly associated with postoperative change in IIEF-5 score (P = 0.02). A post hoc analysis of the association revealed that patients with one risk factor were significantly more likely to have increased IIEF-5 scores (N = 18), whereas those with two or more risk factors were significantly more likely to have decreased IIEF-5 scores (N = 21, P < 0.05). Furthermore, those with no risk factors were significantly more likely to be stable (N = 8) compared with those with more than two risk factors, who were more likely to have decreased scores (P < 0.05). The hierarchical logistic regression results showed that when examining all risk factors simultaneously, because of multicollinearity, only hyperlipidemia was significantly associated with postoperative ED (odds ratio [OR] = 11.33, confirdence interval [CI] = 1.25, 102.82). Frequency of intercourse was also significantly associated with postoperative ED after controlling for risk factors (OR = 0.71, CI = 0.52, 0.97).ConclusionsThis data clearly shows that the number of cardiovascular risk factors is an essential predictive factor for sexual function following surgery. Only hyperlipidemia may play a predictive role for the future sexual function of patients undergo CABG. Mohamed OA, Hamed HA, Roaiah MF, Helmy T, Mahran A, and Bennett CJ. Vascular risk factors as predictors of sexual function following coronary artery bypass graft. J Sex Med 2009;6:2017–2023. |
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