耐碳青霉烯类鲍曼不动杆菌同源性研究

目的 探讨我院2001年8月～2002年3月显著增多的耐碳青霉烯类鲍曼不动杆菌之间的同源性。方法 用脉冲场凝胶电泳对7株耐碳青霉烯类鲍曼不动杆菌进行分型，明确其是否为同一菌株的克隆。结果 7株不动杆菌分为：A型2株，A1型2株，A2型1株。A1型与A2型之间的相似系数达94．6％，它们与A型的相似系数达84．9％，其余两株各有独特的PFGE分型。结论 其中5株耐碳青霉烯类鲍曼不动杆菌有高度同源性，第5号株极可能是此次院内感染的源头。

The Homogeneity of Carbapenem-resistant Acinetobacter Baumannii

Objective To investigate the homogeneity of the unusually ever-increasing carbapenm-resistant(CR)Acinetobacer baumannii isolates selected from August 2001 to March 2002 in Shenzhen People's Hospital.Methods The pulse-field gel electrophoresis(PFGE) was used to type 7 CR Acinetobacter isolates gathered in our hospital,determing whether they derived from the same clone or not.Result 7 isolates was identified to these PFGE types :2 for type A,2 for type A1,1 for type A2.The similarity coeffient between A1 and A2 was 94.6%, 84.9% between A1(A2) and A .The other two isolates showed distinct PFGE types.Conclusion The five CR Acinetobacter baumannii isolates were closely related.The finding highly suggests that V isolate is the source of the nosocomial infection.