| 百岁老人抗氧化机能观察 |
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| 引用本文： | 郑志学 章谷生. 百岁老人抗氧化机能观察[J]. 中国老年学杂志, 1994, 14(6): 331-333 |
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| 作者姓名： | 郑志学 章谷生 |
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| 作者单位： | 上海市老年医学研究所，上海市老年医学研究所，上海市老年医学研究所，上海市老年医学研究所，上海第二医科大学检验系，上海市静安区医学化验所 上海 200040，上海 200040，上海 200040，上海 200040 |
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| 摘 要： | 29例百岁老人检测抗氧化机能三种酶、红细胞SOD、血清CAT、GSH以及LPO,26例百岁老人检测发硒。结果表明百岁老人LPO明显低于老年组,SOD与对照组相似,CAT低于对照组,GSH在正常范围内。百岁老人发硒和老年组、青壮年组亦无差异,LPO保持低水平状态可能是减少老年性疾病发生机理之一,SOD和LPO呈明显负相关(r=-0.4672),SOD和TNF呈明显正相关(r=0.6079),说明百岁老人具有较强的抗氧化机能来消除自由基,上述各因素可能是延缓衰老而致长寿的因素之一。
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| 关 键 词： | 百岁老人 抗氧化机能 SOD CAT GSH LPO 发硒 |
Survey of antioxidation capacity in Centenarians |
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| long Zhixue,Zhang Gusheng,Zhu Qinghuei,et al. Survey of antioxidation capacity in Centenarians[J]. Chinese Journal of Gerontology, 1994, 14(6): 331-333 |
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| Authors: | long Zhixue Zhang Gusheng Zhu Qinghuei et al |
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| Affiliation: | Institute of Geriatrics of Shanghai. Shanghai 200040 |
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| Abstract: | The enzymes of antioxidation such as superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) and lipid peroxide (LPO) levels were measured in 29 centenarians. The selenium (Se) of hair in 26 centenarians were examined and compared with aged and youth group. The results showed that the decreased LPO were found in centenarians; SOD were similar to control group with lower CAT. GSH were in normal levels. The Selenium of hair in Centenarians were similar with no significant difference as compared with elderly and youth group. The relationship between SOD and LPO; r=-0. 4672, SOD TNFa;r = 0. 6079. The decreased LPO levels in centenarians were important because it played a role to reduce some senile disease. Centenarians possess better antioxidation capacity to scavenge free radicals, that may lead centenarians in good health and longevity. |
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| Keywords: | Centenarians Antioxidation capacty |
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